Defence Minister Israel Katz said Israel struck the largest petrochemical facility at Asaluyeh in Iran on Monday.
Katz made the announcement in a video statement.
He noted the site produces about half of the country’s petrochemical output.
Israel also struck the Mahshahr Petrochemical Special Zone in southwest Khuzestan province on Saturday.
A local Iranian official said five people died in that attack.
The two sites together handle roughly 85 per cent of Iran’s petrochemical exports.
Katz said they no longer function. He added that the action deals an economic loss of tens of billions of dollars to Iran.
Israel carried out strikes on gas facilities in the South Pars area of Asaluyeh last month as well.
In recent days the country targeted several industrial sites in its campaign against Iran.
On Friday Prime Minister Benjamin Netanyahu said the strikes reduced Iran’s steel production capacity by 70 per cent.
Steel serves as a key material for weapons, drones and ships.
Katz said he and Netanyahu ordered the military to keep striking Iran’s national infrastructure.
